Interleukin-6 - A Key Regulator of Colorectal Cancer Development

Evaluation of preoperative elevation of serum c-reactive protein as an indicator for prognosis of colorectal cancer

  Abstract   Background : Cancer has not been elucidated in colerectal site. C-reactive protein   (CRP) is a product synthesized in hepatocytes and has been reported to be up-regulated   by such proinflammatory cytokines as interleukin-1 (IL-1), interleukin-6 (IL-6),   and tumor necrosis factor (TNF). The significance of a preoperative serum elevation   was evaluated using CRP as a predictive i...

Association of interleukin-1 gene polymorphism with risk of gastric and colorectal cancers in an Iranian population

Linkage between Large intergenic non-coding RNA regulator of reprogramming and Stemness State in Samples with Helicobacter pylori Infection of Gastric Cancer Cells

Background: Long noncoding RNAs (lncRNAs), as non-protein coding transcripts, play key roles in tumor progression and stemness state in many malignancies, as their aberrant expression has been found in gastric cancer (GC) as one of the most common cancer worldwide. LINC-ROR (large intergenic noncoding RNA regulator of reprogramming) identified as an involved lncRNA in human malignancies, howeve...

The Role of Angiogenesis in Colorectal Polyps and Cancer, a Review

ABSTRACT           Colorectal cancer remains a leading cause of morbidity and mortality worldwide. Most colorectal cancers begin as a growth of tissue called a polyp, some types of which can change into cancer over the course of several years. Angiogenesis, the formation of new blood vessels, is known to play a key role in the initiation, growth and...

THE BURDEN OF PREMATURE MORTALITY DUE TO COLORECTAL CANCER IN GOLESTAN PROVINCE FROM 2011 – 2015: A SEQUENTIAL CROSS-SECTIONAL STUDY

Background & Aims: The burden of premature mortality is used to prioritize health problems. The purpose of this study was to estimate the burden of premature mortality due to colorectal cancer in Golestan from 2011 – 2015. Materials & Methods: In this sequential cross-sectional study, based on the province mortality registration data and standard expected years of life lost (SEYLL), the burden...